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5008S CorDiax

HDF pump

HighVolumeHDF as easy as HD

  • AutoSub plus: automatically maximising substitution volume for HighVolumeHDF
  • Venous Access Monitor (VAM): optimised monitoring of the venous path
  • Easy handling
  • Efficient and sustainable

HighVolumeHDF as standard

With the AutoSub plus function of the 5008S HighVolume,HDF becomes as simple and reliable as HD without any additional need for user interaction.

5008S CorDiax

5008S CorDiax

Opening a world of possibilities

The 5008S CorDiax enables HighVolumeHDF as a standard in dialysis thanks to AutoSubplus, for automatically maximised substitution volumes and the Venous Access Monitor (VAM), for the increased probability of early detection of needle dislodgement.

An older man and older woman standing together, smiling

HighVolumeHDF therapy

HighVolumeHDF : the standard in cardioprotective Haemodialysis (HD)

In order to achieve the full benefits of HDF therapy, large convective volumes are required in post-dilution mode. In the past, many users were concerned that these high volumes may lead to excessive haemoconcentration and subsequently, high transmembrane pressures if the treatment settings were not continuously monitored and adjusted.

AutoSub plus: automatically maximising substitution volume for HighVolumeHDF

The innovative AutoSub plus system is much more than just another automatic pressure control:
Very precise information on the conditions in the dialyser is available, not just across the membrane, but also along the blood flow pathway
Several checks per minute enable the continuous optimisation of the substitution rates
The system is automatically activated at the start of the treatment
AutoSub plus supports the nephrologist in establishing HighVolumeHDF as standard therapy.

Insight and continuity make the difference

While other systems check and adjust the Transmembrane Pressure (TMP) at defined time intervals, AutoSub plus measures and evaluates the conditions directly inside the filter several times per minute. The innovative technology behind it is based on a dynamic signal analysis of pressure pulses. As a result, substitution volumes can be maximised individually for every patient without any user interaction.

The VAM increases the probability of early detection of venous needle dislodgement

Safety creates confidence

In particular, during HighVolumeHDF, blood flows are desired, monitoring of the venous access is essential, as a blood loss would become critical within a very short time. The 5008S CorDiax offer a sophisticated safety feature as standard in all machines to minimise the risk of external blood loss:

Venous Access Monitor (VAM): optimised monitoring of the venous path

VAM is a unique and intelligent safety feature. It enables dynamic and highly sensitive monitoring of the venous pressure by combining arterial and venous pressure signals with an adaptive algorithm.  In this way, VAM is designed to indicate sudden, small drops in venous pressure of approximately 15 mmHg, even when the venous pressure does not exceed the lower alarm limit.   VAM was developed to support healthcare professionals in the early detection of venous needle dislodgement. VAM also includes an alarm management system. An alarm is activated if the monitored signals show exceptional or abnormal variations from the previous pressure profile.

If an alarm is emitted, the blood pump is stopped immediately and the venous clamp is closed. This gives the nursing staff more time to react appropriately to critical pressure changes.

Easy handling

ONLINEplus: reducing workload, increasing usage

Historically, the required amounts of substitution fluid had to be provided in infusion bags. This added to the workload of the nursing staff and deterred dialysis centres from using HDF. In order to give more patients access to the benefits of HDF, we have developed a dialysis system which prepares the substitution fluid directly at the bedside: the ONLINEplus system. Based on the highly reliable two-stage filtration process, ONLINEplus facilitates the online production of sterile and nonpyrogenic substitution fluid very cost-efficiently. Online haemodiafiltration was born.

Blood lines

Our innovative blood lines were developed based on the idea that HighVolumeHDF should be as easy and safe to deliver as any other type of HD. With a standard set-up of a 5008S CorDiax, you can already perform HighVolumeHDF.

Efficient and sustainable

It is not only the advanced treatment options that make the 5008S CorDiax series unique, but also its eco-friendliness, Fresenius Medical Care supports the sensible and sustainable use of resources by saving dialysate, water and energy. This in turn leads to significant cost savings.

  • ONLINEplus technology for the production of sterile, endotoxin-free and  bicarbonate-buffered electrolyte solutions1
    • Extensive amounts of substitution fluid are available for HDF
    • No more need for ready-made rinse solutions: priming, re-infusion and bolus with ONLINE fluid are possible in all treatment modes (also in HD)2
  • AutoFlow automatically adjusts the dialysate flow rate to the effective blood flow rate during treatment
    • Substantial savings of water, waste water, concentrates and energy, leading to significant cost reductions
    • Automatic selection of AutoFlow factor based on treatment mode, always accomplishing an optimal ratio between economic considerations and treatment quality
  • EcoFlow for minimised dialysate and energy consumption during preparation and after re-infusion while avoiding bacterial growth

If you would like to order this product via the NHS Supply Chain Catalogue, please visit the following link: NHS Supply Chain Online Catalogue

Additional information relating to multiBic or Calrecia can be found in the critical care section of our product information page.

Adverse Events Reporting 

Adverse events should be reported. Reporting forms and information can be found at or search for MHRA Yellowcard in the Google Play or Apple app store. Adverse events should also be reported to Fresenius Medical Care on 01623 445100.

UK/HEMA/FME/0922/0005 Date of Preparation: November 2022

Related content

HighVolumeHDF is Fresenius Medical Care.

6008 CAREsystem: Fresenius Medical Care

More care. Less complexity.

1 In accordance with ISO 23500:2011 and ISO 11663:2009

2 Safety advice: It is recommended that you stock sodium chloride in case it might be required

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